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GSK3beta (Phospho-Ser9)
GSK3beta (Phospho-Ser9)
- 中文名称：
- GSK3beta (Phospho-Ser9)
- 英文名称：
- GSK3beta (Phospho-Ser9)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47786
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody is stable for at least one (1) year at -20 degree C. Can be stored at 4 degree C for short-term.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- N/A
- 应用：
- IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:This antibody detects endogenous human, mouse, and rat GSK3 beta only when phosphorylated at serine 9.
纯度:N/A
形式：100ul at 1.0mg/ml in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Affinity-purified on phosphopeptide; non-phosphopeptide- reactive antibodies were removed by chromatography on non-phosphorylated peptide.
浓度：N/A
- 说明书：
GSK3beta participates in the Wnt signaling pathway and is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3beta phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. It also phosphorylates CTNNB1/beta-catenin and MUC1 in breast cancer cells and decreases the interaction of MUC1 with CTNNB1/beta-catenin.
