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p53
p53
- 中文名称:
- p53
- 英文名称:
- p53
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60499
- 规格:
- 0.25 mg|2x0.25 mg|3x0.25 mg|4x0.25 mg|5x0.25 mg
- 保存建议:
- Stored at -20°C. Aliquot to avoid freeze/thaw cycles
- 货期:
- 6-8周
- 来源宿主:
- Sheep
- 反应种属:
- Human, Mouse, Rat
- 应用:
- IS (Immunostaining), IP (Immunoprecipitation), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Ammonium Sulfate Precipitation
形式:Provided as solution in phosphate buffered saline with 0.08% sodium azide
浓度:N/A
- 说明书:
P53 is a transcription factor with a molecular weight of 53kDa that can inhibit cell cycle progression or induce apoptosis in response to stress or DNA damage. Disruption of the p53 signalling pathway through various mechanisms is the most common alteration in human cancer occuring in over half of all tumors. The p53 protein is short lived and expressed at low levels in normal cells but accumulates and/or is activated in cells that have undergone genotoxic damage or oncogene activation. Many tumor derived and transformed cell lines express elevated levels of mutant p53 protein.