![Anti-Glypican 3 [4G7]](/skin/notimg.webp)
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Anti-Glypican 3 [4G7]
Anti-Glypican 3 [4G7]
- 中文名称:
- Anti-Glypican 3 [4G7]
- 英文名称:
- Anti-Glypican 3 [4G7]
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA72397
- 规格:
- 0.2 mg|2x0.2 mg|3x0.2 mg|4x0.2 mg|5x0.2 mg
- 保存建议:
- Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
- 货期:
- 6-8周
- 来源宿主:
- N/A
- 反应种属:
- Human
- 应用:
- IHC (Immunohistochemistry), ELISA, FCM/FACS (Flow Cytometry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:N/A
同型:Rabbit IgG kappa
克隆号:[4G7]
特异性:This antibody binds an epitope spanning the furin cleavage site at amino acids R358/S359 of human GPC3. Glypican-3 is an oncofetal antigen that belongs to the glypican family of glycosyl-phosphatidylinositol-anchored heparin sulfate proteoglycans. It negatively regulates the hedgehog signaling pathway and positively regulates the canonical Wnt signaling pathway. Multiple studies have revealed that GPC-3 is overexpressed in hepatocellular carcinoma (HCC).
纯度:Purified. Protein A affinity purified
形式:PBS with 0.02% Proclin 300.
浓度:1mg/ml
- 说明书:
The original antibody was generated by immunizing BALB/c mice with a recombinant human GPC3 extracellular domain (ECD, amino acids of 1-547) fused to a C-terminal DYKDDDDK (RADYKDDDDK).
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.