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CDC42, 1- 188aa, Human, T7-tag, E Coli
CDC42, 1- 188aa, Human, T7-tag, E Coli
- 中文名称：
- CDC42, 1- 188aa, Human, T7-tag, E Coli
- 英文名称：
- CDC42, 1- 188aa, Human, T7-tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48564
- 规格：
- 0.02 mg|0.1 mg|0.5 mg|5x0.02 mg|5x0.1 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- CAS号：
- 485-64-3
- 纯度：
- > 95% by SDS-PAGE
- 产品形式：
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA
- 分子量：
- 296.41 g/mol
- 分子式：
- C19H24N2O
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Cell division cycle 42 isoform 1, also known as CDC42, is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. Also, this protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Loss of CDC42 function caused an increase in the endocytotic uptake of apical proteins, including apical polarity factors such as Crumbs. Recombinant human CDC42, fused to T7-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
