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TK1, 1-234aa, Human, His tag, E Coli
TK1, 1-234aa, Human, His tag, E Coli
- 中文名称：
- TK1, 1-234aa, Human, His tag, E Coli
- 英文名称：
- TK1, 1-234aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48751
- 规格：
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议：
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- CAS号：
- 487-51-4
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
- 分子量：
- 182.22 g/mol
- 分子式：
- C10H14O3
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
TK1, also known as thymidine kinase, is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase. It is present in two forms in mammalian cells, TK1 and TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Deoxythymidine is present in the body fluids as a result of degradation of DNA from food and from dead cells. Thymidine kinase is required for the action of many antiviral drugs. It is used to select hybridoma cell lines in production of monoclonal antibodies. In clinical chemistry it is used as a proliferation marker in the identification, control of treatment and follow-up of malignant disease, mainly of hematological malignancies. Recombinant human TK1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
