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MOUSE ANTI PIG CD3: FITC
MOUSE ANTI PIG CD3: FITC
- 中文名称：
- MOUSE ANTI PIG CD3: FITC
- 英文名称：
- MOUSE ANTI PIG CD3: FITC
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA50259
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Pig
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[PPT3]
特异性:CD3
纯度:N/A
形式：Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
浓度：IgG concentration 0.1 mg/ml
- 说明书：
Mouse anti Pig CD3, clone PPT3 recognizes the porcine homologue of human CD3epsilon, a 24 kDa single pass type I membrane protein expressed by T-lymphocytes. Clone PPT3, also known under the clone designation FY1H2, was clustered at the second international swine CD workshop and found to specifically recognise an epitope on the porcine CD3epsilon designated as CD3c (Pescovitz, M.D., et al. 1998).CD3 is a multimeric protein complex composed of four distinct polypeptide chains (epsilon, gamma, delta, zeta) that assemble and function as three pairs of dimers (epsilongamma, epsilondelta, zetazeta). The CD3 complex serves as a T cell co-receptor that associates non-covalently with the T cell receptor (TCR) (Guy, C.S & Vignali, D.G. 2009). CD3 is a defining feature of cells belonging to the T cell lineage, antibodies recognising pig CD3 therefore provide useful markers of porcine T cells. Clone PPT3 has been demonstrated to recognise an epitope that is expressed both intracellularly and extracellularly, additionally clone PPT3 has been demonstrated to activate alpha/beta T-cells (Kirkham P.A., et al. 1996). Epitope mapping studies have demonstrated that clone PPT3 recognises an alternative epitope to clone PPT6 (Yang, H. et al. 1996; Pescovitz, M.D., et al. 1998). Clone PPT3 was tested on PBL from a range of other mammalian species and found to be negative suggesting that the epitope recognised by this clone is specific to porcine (Yang, H. et al. 1996).
