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Goat Polyclonal to Human PDGF-BB / PDGFB
Goat Polyclonal to Human PDGF-BB / PDGFB
- 中文名称:
- Goat Polyclonal to Human PDGF-BB / PDGFB
- 英文名称:
- Goat Polyclonal to Human PDGF-BB / PDGFB
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA52079
- 规格:
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议:
- Store at -20 degree C. Minimize freezing and thawing.
- 货期:
- 6-8周
- 来源宿主:
- Goat
- 反应种属:
- Reactivity: Human, Bovine, Sheep
Predicted Reactivity:Monkey, Mouse, Rat, Bat, Dog, Horse.
- 应用:
- IHC (Immunohistochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:Human PDGFB.
纯度:Immunoaffinity Purified
形式:Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
浓度:0.5 mg/ml
- 说明书:
PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.