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Adenylate Cyclase III/ADCY3
Adenylate Cyclase III/ADCY3
- 中文名称：
- Adenylate Cyclase III/ADCY3
- 英文名称：
- Adenylate Cyclase III/ADCY3
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA76703
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for sixmonths without detectable loss of activity. The antibody can be stored at 2 degree - 8 degree C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Chicken
- 反应种属：
- Mouse, Rat
- 应用：
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:N/A
形式：Liquid. Affinity purified antibody at 1.0mg/mL in 50% PBS, 50%glycerol plus 5mM NaN3
浓度：N/A
- 说明书：
Trimeric G-proteins are a large and variable family of membrane receptors. On binding their specific ligand they activate specific members of the family of trimeric G-proteins which in turn activate other signalling enzymes. Adenylate cyclases are one of these downstream enzyme families which are activated by the GTP bound GalphaS subunits of trimeric G-proteins. Adenylate cyclases are responsible for the production of the important "second messenger" signaling molecule cyclic-AMP which in turn activates the cAMP dependent protein kinase, which phosphorylates and regulates numerous other molecules. There are several different adenylate cyclase gene products, the type III adenylate cyclase being specifically localized in neuronal cilia. Much interest has focused on neuronal cilia since they express a variety of receptors and appear to function as a unique and previously not well understood sensory structure of neurons. For examples, the somatostatin 3 receptor, NPY2 receptor and melanin concentrating hormone receptor 1 are localized in neuronal cilia and the sonic hedgehog and Wnt signalling pathway act primarily through neuronal cilia. This antibody is an excellent marker of neuronal cilia in the brain and in cells in tissue culture and works in the same way as our rabbit polyclonal made against the same peptide.
This antibody was made against the C-terminal peptide of rat ACIII, works on mouse and human cells and is an excellent marker of neuronal cilia in the brain and in cells in tissue culture.
