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COX-1 Antibody
COX-1 Antibody
- 中文名称：
- COX-1 Antibody
- 英文名称：
- COX-1 Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA111069
- 规格：
- 0.1 mL|0.1 mL (FITC)|0.1 mL (AF568)|0.1 mL (AF555)|0.1 mL (AF488)
- 保存建议：
- Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- N/A
- 反应种属：
- Human, Mouse
- 应用：
- ICC (Immunocytochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of COX-1.
纯度:Affinity purified
形式：1*TBS (pH7.4), 0.5%BSA, 25% Glycerol.
浓度：N/A
- 说明书：
Cyclooxygenase-1(Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid. Cox1 is expressed constitutively in most tissues, while Cox2 expression is induced by lipopolysaccaride (LPS) and peptoglycan (PGN). PGN activates Ras, leading to phosphorylation of Raf at Ser338 and Erk 1/2 at Tyr204). Both Cox1 and Cox2 play a role in the neuropathology of Alzheimer's disease by potentiating gamma-secretase activity and beta-amyloid generation. Pharmacological inhibition of COX can provide relief from the symptoms of inflammation and pain.
