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ATP-Citrate Lyase (ACLY) Antibody
ATP-Citrate Lyase (ACLY) Antibody
- 中文名称:
- ATP-Citrate Lyase (ACLY) Antibody
- 英文名称:
- ATP-Citrate Lyase (ACLY) Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA111291
- 规格:
- 0.1 mg|0.1 mL (AF647)|0.1 mL (AF594)|0.1 mL (HRP)|0.1 mL (PE)
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG2a
克隆号:N/A
特异性:This antibody detects endogenous levels ATP-Citrate Lyase and does not cross-react with related proteins.
纯度:Affinity purified
形式:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
浓度:N/A
- 说明书:
UniPort Summary Function: ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
Entrez Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440, 000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.