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Podocalyxin; GCTM-2 antigen; Gp200; PC; PODXL; PCLP; PCLP1
Podocalyxin; GCTM-2 antigen; Gp200; PC; PODXL; PCLP; PCLP1
- 中文名称：
- Podocalyxin; GCTM-2 antigen; Gp200; PC; PODXL; PCLP; PCLP1
- 英文名称：
- Podocalyxin; GCTM-2 antigen; Gp200; PC; PODXL; PCLP; PCLP1
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA18868
- 规格：
- 0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议：
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human. Other species are not tested. Please decide the specificity by homology
- 应用：
- ELISA, IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b
克隆号:N/A
特异性:Specific for PODXL denatured and native forms
纯度:>95%, Protein G Purified
形式：Liquid
浓度：N/A
- 说明书：
Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
