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Anti-SHP1/PTPN6 Antibody Picoband (monoclonal, 8H11B10)
Anti-SHP1/PTPN6 Antibody Picoband (monoclonal, 8H11B10)
- 中文名称:
- Anti-SHP1/PTPN6 Antibody Picoband (monoclonal, 8H11B10)
- 英文名称:
- Anti-SHP1/PTPN6 Antibody Picoband (monoclonal, 8H11B10)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA19675
- 规格:
- 0.01 mg|0.1 mg|0.1 mg (Carrier Free)|0.1 mg (HRP)|0.1 mg (FITC)
- 保存建议:
- Store at -20 degree C for one year from date of receipt. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for six months. Avoid repeated freezing and thawing.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human, Mouse, Rat
- 应用:
- FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), ICC (Immunocytochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:Mouse IgG2b
克隆号:[8H11B10]
特异性:N/A
纯度:Immunogen affinity purified.
形式:Lyophilized
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
浓度:Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
- 说明书:
Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.