
-
Elf3 antibody - N-terminal region
Elf3 antibody - N-terminal region
- 中文名称:
- Elf3 antibody - N-terminal region
- 英文名称:
- Elf3 antibody - N-terminal region
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA198138
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- 短期使用时,在2-8摄氏度下储存一周。对于长期储存,以小份储存在-20摄氏度,以防止冻融循环。
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Mouse, Rat
- 应用:
- WB (Western Blot), IHC (Immunohistochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:Affinity Purified
形式:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
浓度:N/A
- 说明书:
This is a rabbit polyclonal antibody against Elf3. It was validated on Western Blot and immunohistochemistry
Target Description: Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.