
-
ESR1 antibody - middle region
ESR1 antibody - middle region
- 中文名称:
- ESR1 antibody - middle region
- 英文名称:
- ESR1 antibody - middle region
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA199568
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- 短期使用时,在2-8摄氏度下储存一周。对于长期储存,以小份储存在-20摄氏度,以防止冻融循环。
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Cow, Dog, Human, Pig, Rat, Sheep
- 应用:
- WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:Affinity Purified
形式:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
浓度:N/A
- 说明书:
This is a rabbit polyclonal antibody against ESR1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.