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SLC27A2 Polyclonal Antibody (Human)
SLC27A2 Polyclonal Antibody (Human)
- 中文名称：
- SLC27A2 Polyclonal Antibody (Human)
- 英文名称：
- SLC27A2 Polyclonal Antibody (Human)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA201886
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- 储存在-20摄氏度
- 货期：
- 6-8周
- 来源宿主：
- N/A
- 反应种属：
- Human
- 应用：
- ICC (Immunocytochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Protein A
形式：PBS w/ 0.09% sodium azide
浓度：1mg/ml
- 说明书：
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes, playing an important role in hepatic fatty acid uptake (PubMed:20530735, PubMed:22022213, PubMed:24269233, PubMed:10198260, PubMed:10749848, PubMed:11980911). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:20530735, PubMed:22022213, PubMed:24269233, PubMed:10198260, PubMed:10749848, PubMed:11980911).Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis (PubMed:20530735).Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid (PubMed:10198260).May contribute to the synthesis of sphingosine-1-phosphate (PubMed:24269233).Does not activate C24 bile acids, cholate and chenodeoxycholate (PubMed:11980911).In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol (PubMed:11980911).However, it is not critical for THCA activation and bile synthesis in vivo (PubMed:20530735).
