
-
Rabbit anti-CRM1 Antibody, Affinity Purified
Rabbit anti-CRM1 Antibody, Affinity Purified
- 中文名称:
- Rabbit anti-CRM1 Antibody, Affinity Purified
- 英文名称:
- Rabbit anti-CRM1 Antibody, Affinity Purified
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA210970
- 规格:
- 0.01 mg|0.1 mg|5x0.01 mg|2x0.1 mg|3x0.1 mg
- 保存建议:
- 储存在2-8摄氏度下< br >保质期:自收到之日起1年
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Mouse
- 应用:
- IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:Antigen Affinity Purified
形式:Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
浓度:1000ug/ml
- 说明书:
Chromosome region maintenance 1 protein homolog (CRM1) is the Ran-GTP-binding nuclear export receptor for proteins bearing a leucine rich nuclear export signal and RNAs. CRM1 also possesses a mitotic function as it localizes to kinetochores, and with Ran-GTP, recruits Ran-GTPase-activating protein (Ran-GAP1) and Ran-binding protein (Ran-BP2) for proper mitotic spindle assembly and chromosome segregation. Additionally, CRM1 is suggested to function as a loading dock of various cell cycle and checkpoint factors such as cyclins, Cdks, p53 and BRCA1, to regulate proper chromosome duplication and genomic stability.