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Rabbit anti-Sin1 Antibody, Affinity Purified
Rabbit anti-Sin1 Antibody, Affinity Purified
- 中文名称:
- Rabbit anti-Sin1 Antibody, Affinity Purified
- 英文名称:
- Rabbit anti-Sin1 Antibody, Affinity Purified
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA211214
- 规格:
- 0.01 mg|0.1 mg|5x0.01 mg|2x0.1 mg|3x0.1 mg
- 保存建议:
- 储存在2-8摄氏度下< br >保质期:自收到之日起1年
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 应用:
- IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:Antigen Affinity Purified
形式:Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
浓度:1000ug/ml
- 说明书:
Stress-activated map kinase-interacting protein 1 (Sin1) is highly similar to the yeast stress- activated protein kinase SIN1. Sin1 is an essential mTORC2 subunit that is required to act as the PDK2 that phosphorylates Akt/PKB at Ser 473. Sin1 has been implicated as a scaffolding protein. Sin1 is required for rictor binding in the mTORC2 complex. Sin1 has also been shown to be important to the SAPK (stress-activated kinase) signaling pathway and in the nucleus may act as a scaffold between ATF-2 and p38 to facilitate p38-induced phosphorylation of ATF-2. Sin1 is also found to form a complex with c-Jun N-terminal kinase (JNK) and may similarly function as a scaffolding protein in JNK signaling.