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Rabbit anti-CIP2A Antibody, Affinity Purified
Rabbit anti-CIP2A Antibody, Affinity Purified
- 中文名称:
- Rabbit anti-CIP2A Antibody, Affinity Purified
- 英文名称:
- Rabbit anti-CIP2A Antibody, Affinity Purified
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA211480
- 规格:
- 0.01 mg|0.1 mg|5x0.01 mg|2x0.1 mg|3x0.1 mg
- 保存建议:
- 储存在2-8摄氏度下< br >保质期:自收到之日起1年
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 应用:
- IHC (Immunohistochemistry), IP (Immunoprecipitation)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:Antigen Affinity Purified
形式:Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
浓度:1000ug/ml
- 说明书:
CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.