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Anti-RAB18 Antibody, Rabbit Polyclonal
Anti-RAB18 Antibody, Rabbit Polyclonal
- 中文名称：
- Anti-RAB18 Antibody, Rabbit Polyclonal
- 英文名称：
- Anti-RAB18 Antibody, Rabbit Polyclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258532
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Human RAB18
纯度:Protein A & Antigen Affinity
形式：Liquid; PBS, pH7.0 with 0.03% Proclin300
浓度：N/A
- 说明书：
Rab18 is one of the small numbers of conserved Rab proteins that have been traced to the last eukaryotic common ancestor. It is found in organisms ranging from humans to trypanosomes and localizes to multiple organelles, including most notably endoplasmic reticulum (ER) and lipid droplets (LDs). Rab18, a small Rab GTPase, regulates intracellular membrane-trafficking events between various compartments in cells and is involved in the life cycle of multiple viruses. In humans, the absence of Rab18 leads to a severe illness known as Warburg micro syndrome (WARBM), whose clinical features include vision impairment, postnatal microcephaly, and lower limb spasticity. The functions of RAB18 and RAB7 in lysosomal and autophagic activities may constitute an overlapping mechanism underlying WARBM and CMT pathogenesis in the nervous system.
