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Anti-RRM2 Antibody, Rabbit Polyclonal
Anti-RRM2 Antibody, Rabbit Polyclonal
- 中文名称:
- Anti-RRM2 Antibody, Rabbit Polyclonal
- 英文名称:
- Anti-RRM2 Antibody, Rabbit Polyclonal
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA258535
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 应用:
- IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Human RRM2
纯度:Protein A & Antigen Affinity
形式:Liquid; 0.2um filtered solution in PBS
浓度:N/A
- 说明书:
Ribonucleotide reductase M2 (RRM2) is one of the two subunits that comprise ribonucleotide reductase (RR), the enzyme that catalyzes the conversion of ribonucleotide 5'?diphosphates into 2'?deoxyribonucleotides, which are required for DNA synthesis. RRM2 is a stress response factor important for the development of several tumors. RRM2 may be involved in the proliferation and apoptosis of MM cells via the Wnt/beta?catenin signaling pathway, suggesting that RRM2 may represent a novel therapeutic target for MM. RRM2 plays vital roles in many cellular processes such as cell proliferation, invasiveness, migration, angiogenesis, senescence, and tumorigenesis. RRM2 is essential for DNA synthesis and DNA repair by producing dNTPs. It is frequently overexpressed in cancers, but very little is known about its function in prostate cancer.