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Anti-UBQLN2 Antibody, Rabbit Polyclonal
Anti-UBQLN2 Antibody, Rabbit Polyclonal
- 中文名称：
- Anti-UBQLN2 Antibody, Rabbit Polyclonal
- 英文名称：
- Anti-UBQLN2 Antibody, Rabbit Polyclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258537
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Human UBQLN2
纯度:Protein A & Antigen Affinity
形式：Liquid; PBS, pH7.0 with 0.03% Proclin300
浓度：N/A
- 说明书：
Ubiquilin-2 (UBQLN2) is a 66?kDa protein member of the ubiquilin family. UBQLN2 has a ubiquitin-like domain (UBL) in its N-terminal that can interact with the proteasome, and a ubiquitin-associated domain (UBA) on the C-terminal which recognizes the polyubiquitin chains on marked proteins. UBQLN2 contains four stress-induced protein 1-like domains (STI-1 like), located between the residues 178-247 and 379-462, which are involved in the interaction with heat-shock proteins and autophagy mediators. UBQLN2 has also a unique PXX domain containing 12 tandem repeats implicated in protein-protein interactions. This domain differentiates UBQLN2 from other members of the ubiquilin family. UBQLN2 plays an essential role in noxious protein accumulation and clearance pathways in amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) pathogenesis.
