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Anti-VAMP8 Antibody, Rabbit Polyclonal
Anti-VAMP8 Antibody, Rabbit Polyclonal
- 中文名称：
- Anti-VAMP8 Antibody, Rabbit Polyclonal
- 英文名称：
- Anti-VAMP8 Antibody, Rabbit Polyclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258544
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IP (Immunoprecipitation), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Human VAMP8
纯度:Protein A & Antigen Affinity
形式：Liquid; PBS, pH7.0 with 0.03% Proclin300
浓度：N/A
- 说明书：
VAMP8 (also known as endobrevin), a member of the soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) family of fusion proteins, initially characterized in endosomal and endosomal-lysosomal fusion, may also function in regulated exocytosis. VAMP8 gene plays an important role in biological functions like endosomal fusion, sequential granule-to-granule fusion, and autophagy. The VAMP8 vesicle-associated-SNARE is required for the proper trafficking of secretory lysosomal granules for exocytosis in macrophages and the release of the potent pro-inflammatory cytokine, TNF-alpha. The VAMP8 acts as a novel oncogene by promoting cell proliferation and therapeutic resistance in glioma. VAMP8 is significantly upregulated in human breast cancer (BC) tissues and can thus be a practical and potentially effective surrogate marker for survival in BC patients.
