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Anti-Carbonic Anhydrase IX/CA9 Antibody, Mouse Monoclonal
Anti-Carbonic Anhydrase IX/CA9 Antibody, Mouse Monoclonal
- 中文名称:
- Anti-Carbonic Anhydrase IX/CA9 Antibody, Mouse Monoclonal
- 英文名称:
- Anti-Carbonic Anhydrase IX/CA9 Antibody, Mouse Monoclonal
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA258747
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- 此类产品特殊,请按照说明书指示
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- IHC (Immunohistochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:Mouse IgG1
克隆号:[#09]
特异性:Human Carbonic Anhydrase IX/CA9
纯度:Protein A
形式:Liquid; 0.2um filtered solution in PBS
浓度:N/A
- 说明书:
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3-) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.