-
Anti-ELF3 Antibody, Rabbit Polyclonal
Anti-ELF3 Antibody, Rabbit Polyclonal
- 中文名称：
- Anti-ELF3 Antibody, Rabbit Polyclonal
- 英文名称：
- Anti-ELF3 Antibody, Rabbit Polyclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258752
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IP (Immunoprecipitation), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Human ELF3
纯度:Protein A & Antigen Affinity
形式：Liquid; 0.2um filtered solution in PBS
浓度：N/A
- 说明书：
Chromosomal translocations leading to deregulated expression of ETS transcription factors are frequent in prostate tumors. ESE1/ELF3 was induced by interleukin (IL)-1beta through NF-kappaB and was a crucial mediator of the phenotypic and transcriptional changes induced by IL-1beta in prostate cancer cells. ESE1/ELF3 was overexpressed in human primary and metastatic tumors. E74-like factor 3 (ELF3) protein levels are increased in osteoarthritic (OA) cartilage, that ELF3 accounts for inflammatory cytokine-driven MMP13 gene expression, and that, upon induction by interleukin-1beta, ELF3 binds to the COL2A1 promoter and suppresses its activity in chondrocytes. ELF3 is a favorable prognostic marker for ovarian cancer. As a negative regulator of EMT, ELF3-modulated reversal of EMT may be a new effective modality in the treatment of ovarian cancer.
