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Anti-HUWE1 Antibody, Rabbit Polyclonal
Anti-HUWE1 Antibody, Rabbit Polyclonal
- 中文名称：
- Anti-HUWE1 Antibody, Rabbit Polyclonal
- 英文名称：
- Anti-HUWE1 Antibody, Rabbit Polyclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA259110
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Human HUWE1
纯度:Protein A & Antigen Affinity
形式：Liquid; PBS, pH7.0 with 0.03% Proclin300
浓度：N/A
- 说明书：
HUWE1 (HECT, UBA And WWE Domain Containing E3 Ubiquitin Protein Ligase 1) is a large proteins. There are conflicting reports of the role of HUWE1 in regulating the oncogene c-MYC (MYC). In one model, HUWE1 regulates the stability of MYC through K48-linked ubiquitination and knockdown of HUWE1 leads to increased MYC and drives tumor progression [16]. Conversely, in other tumor types HUWE1 activates transcription of MYC through K63-linked ubiquitination and HUWE1 silencing or inhibition prevents MYC signaling and reduces tumor cell proliferation. HUWE1 may play a cell-type and context-dependent role in MYC regulation.
