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Anti-S100A11 Antibody, Rabbit Polyclonal
Anti-S100A11 Antibody, Rabbit Polyclonal
- 中文名称:
- Anti-S100A11 Antibody, Rabbit Polyclonal
- 英文名称:
- Anti-S100A11 Antibody, Rabbit Polyclonal
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA259126
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Mouse
- 应用:
- IP (Immunoprecipitation), ELISA, WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Mouse S100A11
纯度:Protein A & Antigen Affinity
形式:Liquid; 0.2um filtered solution in PBS
浓度:N/A
- 说明书:
Protein S100-A11, also known as S100 calcium-binding protein A11, S100A11 and MLN70, is a member of theS-100 family. S100A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S100A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferation of the cancer cells. In the nucleus, S100A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S100A11 is also a novel test marker in breast carcinoma.