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Anti-IL-13 R alpha 2/IL13RA2 Antibody, Rabbit Polyclonal
Anti-IL-13 R alpha 2/IL13RA2 Antibody, Rabbit Polyclonal
- 中文名称：
- Anti-IL-13 R alpha 2/IL13RA2 Antibody, Rabbit Polyclonal
- 英文名称：
- Anti-IL-13 R alpha 2/IL13RA2 Antibody, Rabbit Polyclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA259148
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- 此类产品特殊，请按照说明书指示
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Rat
- 应用：
- IHC (Immunohistochemistry), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Rat IL-13 R alpha 2/IL13RA2
纯度:Protein A & Antigen Affinity
IL13RA2/IL13R specific IgG was purified by Rat IL13RA2/IL13R affinity chromatography.
形式：Liquid; 0.2um filtered solution in PBS with 5% trehalose
浓度：N/A
- 说明书：
Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High-Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Ralpha2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Ralpha2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Ralpha2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.
