
-
CDK4 (Cyclin-Dependent Kinase 4, CMM3, MGC14458, PSK-J3) (APC)
CDK4 (Cyclin-Dependent Kinase 4, CMM3, MGC14458, PSK-J3) (APC)
- 中文名称:
- CDK4 (Cyclin-Dependent Kinase 4, CMM3, MGC14458, PSK-J3) (APC)
- 英文名称:
- CDK4 (Cyclin-Dependent Kinase 4, CMM3, MGC14458, PSK-J3) (APC)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA26022
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- N/A
- 应用:
- IF (Immunofluorescence), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1,k
克隆号:[2G7]
特异性:Recognizes CDK4.
纯度:Purified
形式:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
浓度:N/A
- 说明书:
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq]