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STAT5B (Signal Transducer and Activator of Transcription 5B, STAT5) (Biotin)
STAT5B (Signal Transducer and Activator of Transcription 5B, STAT5) (Biotin)
- 中文名称:
- STAT5B (Signal Transducer and Activator of Transcription 5B, STAT5) (Biotin)
- 英文名称:
- STAT5B (Signal Transducer and Activator of Transcription 5B, STAT5) (Biotin)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA26204
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- N/A
- 应用:
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1,k
克隆号:[2D1]
特异性:Recognizes STAT5B.
纯度:Purified
形式:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
浓度:N/A
- 说明书:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq]