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NFkappaB p65 Mouse Monoclonal Antibody
NFkappaB p65 Mouse Monoclonal Antibody
- 中文名称：
- NFkappaB p65 Mouse Monoclonal Antibody
- 英文名称：
- NFkappaB p65 Mouse Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA267145
- 规格：
- 0.1 mg|0.1 mL (AF750)|0.1 mL (HRP)|0.1 mL (AF594)|0.1 mL (AF647)
- 保存建议：
- Store at-20 degree C for 1 year. Do not aliquot the antibody.
- 货期：
- 6-8周
- 来源宿主：
- N/A
- 反应种属：
- Human, Rat, Mouse
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:N/A
克隆号:[5G6]
特异性:NFkappaB p65 Mouse monoclonal antibody detects endogenous p65 proteins.
纯度:N/A
形式：In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：N/A
- 说明书：
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
