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ORC3 Antibody
ORC3 Antibody
- 中文名称：
- ORC3 Antibody
- 英文名称：
- ORC3 Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA267907
- 规格：
- 0.05 mg|0.1 mg|0.1 mL (AF405S)|0.1 mL (AF405L)|0.1 mL (AF546)
- 保存建议：
- Store at -15°C to -25°C for 1 year (Do not lower than -25°C)
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human, Rat, Mouse
- 应用：
- ELISA, WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:ORC3 Polyclonal Antibody detects endogenous levels of protein
纯度:Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
形式：Liquid in PBS containing 50% glycerol and 0.02% sodium azide
浓度：1 mg/ml
- 说明书：
Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
Function: Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the ORC3 family. Subunit: ORC is composed of six subunits.
