![[KO Validated] FGFR2 Rabbit mAb](/skin/notimg.webp)
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[KO Validated] FGFR2 Rabbit mAb
[KO Validated] FGFR2 Rabbit mAb
- 中文名称:
- [KO Validated] FGFR2 Rabbit mAb
- 英文名称:
- [KO Validated] FGFR2 Rabbit mAb
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA282664
- 规格:
- 0.02 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议:
- 储存在-20摄氏度,避免冷冻/解冻循环。
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 应用:
- ELISA, WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Affinity purification
形式:PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
浓度:N/A
- 说明书:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.