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LC3 Antibody (APG8B) (T6)
LC3 Antibody (APG8B) (T6)
- 中文名称:
- LC3 Antibody (APG8B) (T6)
- 英文名称:
- LC3 Antibody (APG8B) (T6)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA286452
- 规格:
- 0.08 mL|0.4 mL|2x0.4 mL|3x0.4 mL|4x0.4 mL
- 保存建议:
- 在2-8摄氏度下冷藏保存6个月。对于长期储存,在-20摄氏度下以小份储存,以防止冻融循环。
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, mouse (Predicted Reactivity: Bovine)
- 应用:
- ELISA, WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:Rabbit Ig
克隆号:N/A
特异性:This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human LC3.
纯度:Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
形式:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
浓度:Vial Concentration: 0.5
- 说明书:
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.