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UMOD Antibody (Center)
UMOD Antibody (Center)
- 中文名称：
- UMOD Antibody (Center)
- 英文名称：
- UMOD Antibody (Center)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA286594
- 规格：
- 0.08 mL|0.4 mL|2x0.4 mL|3x0.4 mL|4x0.4 mL
- 保存建议：
- 在2-8摄氏度下冷藏保存6个月。对于长期储存，在-20摄氏度下以小份储存，以防止冻融循环。
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IHC (Immunohistochemistry), ELISA, WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit Ig
克隆号:N/A
特异性:This UMOD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-380 amino acids from the Central region of human UMOD.
纯度:Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
形式：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
浓度：Vial Concentration: 0.5
- 说明书：
This gene encodes uromodulin, the most abundant protein in
normal urine. Its excretion in urine follows proteolytic cleavage
of the ectodomain of its glycosyl phosphatidylinosital-anchored
counterpart that is situated on the luminal cell surface of the
loop of Henle. Uromodulin may act as a constitutive inhibitor of
calcium crystallization in renal fluids. Excretion of uromodulin in
urine may provide defense against urinary tract infections caused
by uropathogenic bacteria. Defects in this gene are associated with
the autosomal dominant renal disorders medullary cystic kidney
disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy
(FJHN). These disorders are characterized by juvenile onset of
hyperuricemia, gout, and progressive renal failure. While several
transcript variants may exist for this gene, the full-length
natures of only two have been described to date. These two
represent the major variants of this gene and encode the same
isoform.
