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PID/MTA2 Antibody (C-term)
PID/MTA2 Antibody (C-term)
- 中文名称:
- PID/MTA2 Antibody (C-term)
- 英文名称:
- PID/MTA2 Antibody (C-term)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA287022
- 规格:
- 0.08 mL|0.4 mL|2x0.4 mL|3x0.4 mL|4x0.4 mL
- 保存建议:
- 在2-8摄氏度下冷藏保存6个月。对于长期储存,在-20摄氏度下以小份储存,以防止冻融循环。
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, mouse
- 应用:
- WB (Western Blot), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:Rabbit Ig
克隆号:N/A
特异性:This PID/MTA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-544 amino acids from the C-terminal region of human PID/MTA2.
纯度:Purified Rabbit Polyclonal Antibody (Pab)
形式:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
浓度:Vial Concentration: 2
- 说明书:
MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small family of different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.