-
GP6 Antibody (C-term)
GP6 Antibody (C-term)
- 中文名称：
- GP6 Antibody (C-term)
- 英文名称：
- GP6 Antibody (C-term)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA288492
- 规格：
- 0.08 mL|0.4 mL|2x0.4 mL|3x0.4 mL|4x0.4 mL
- 保存建议：
- 在2-8摄氏度下冷藏保存6个月。对于长期储存，在-20摄氏度下以小份储存，以防止冻融循环。
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Rabbit Ig
克隆号:N/A
特异性:This GP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human GP6.
纯度:Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
形式：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
浓度：Vial Concentration: 0.5
- 说明书：
Glycoprotein VI (GP6) is a 58-kD platelet membrane
glycoprotein that plays a crucial role in the collagen-induced
activation and aggregation of platelets. Upon injury to the vessel
wall and subsequent damage to the endothelial lining, exposure of
the subendothelial matrix to blood flow results in deposition of
platelets. Collagen fibers are the most thrombogenic macromolecular
components of the extracellular matrix, with collagen types I, III,
and VI being the major forms found in blood vessels. Platelet
interaction with collagen occurs as a 2-step procedure: (1) the
initial adhesion to collagen is followed by (2) an activation step
leading to platelet secretion, recruitment of additional platelets,
and aggregation. In physiologic conditions, the resulting platelet
plug is the initial hemostatic event limiting blood loss. However,
exposure of collagen after rupture of atherosclerotic plaques is a
major stimulus of thrombus formation associated with myocardial
infarction or stroke (Jandrot-Perrus et al., 2000 [PubMed
10961879]).
