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Cleaved-Integrin alphaV HC (K889) Polyclonal Antibody
Cleaved-Integrin alphaV HC (K889) Polyclonal Antibody
- 中文名称：
- Cleaved-Integrin alphaV HC (K889) Polyclonal Antibody
- 英文名称：
- Cleaved-Integrin alphaV HC (K889) Polyclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA293449
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- 2-8摄氏度，最多2周。对于长期储存，在-20摄氏度下以小份储存，以防止冻融循环。
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:N/A
纯度:N/A
形式：N/A
浓度：N/A
- 说明书：
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV: ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:25398877). ITGAV: ITGB3 and ITGAV: ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D- dependent cell adhesion to FBN1 (PubMed:17158881). Integrin alpha-V/beta-6 or alpha-V/beta-8 (ITGAV: ITGB6 or ITGAV: ITGB8) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:22278742, PubMed:28117447).
