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PSME3 Antibody
PSME3 Antibody
- 中文名称:
- PSME3 Antibody
- 英文名称:
- PSME3 Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA300973
- 规格:
- 0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议:
- 储存在-20摄氏度
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- N/A
- 应用:
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:The antibody detects endogenous level of total PSME3 protein.
纯度:Antibodies were purified by affinity purification using immunogen.
形式:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度:1.0 mg/ml
- 说明书:
The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. PA700, PA28, and PA200 are three major protein complexes that function as activators of the 20S proteasome. There are three evolutionarily conserved subunits of PA28: PA28a (PSME1), PA28b (PSME2), and PA28g (PSME3) (1,2). PA28a and PA28b form a heteroheptameric complex and function by binding to the 20S complex at its opening site(s). The PA28a/b complex is present throughout the cell and participates in MHC class I antigen presentation by promoting the generation of antigenic peptides from foreign proteins (2). PA28g exists in the form of a homoheptamer and is mainly located in the nucleus. The PA28g complex exerts its function by binding and guiding specific nuclear target proteins to the 20S proteasome for further degradation (3,4).