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MLL Monoclonal Antibody
MLL Monoclonal Antibody
- 中文名称:
- MLL Monoclonal Antibody
- 英文名称:
- MLL Monoclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA320159
- 规格:
- 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL
- 保存建议:
- 储存在-20摄氏度/1年
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:N/A
克隆号:N/A
特异性:MLL Monoclonal Antibody detects endogenous levels of MLL protein.
纯度:Affinity purification
形式:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
浓度:N/A
- 说明书:
This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefS