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Akt1 Mouse mAb
Akt1 Mouse mAb
- 中文名称：
- Akt1 Mouse mAb
- 英文名称：
- Akt1 Mouse mAb
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA320352
- 规格：
- 0.04 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL
- 保存建议：
- 储存在-20摄氏度/1年
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Mouse, Transfected
- 应用：
- WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:N/A
克隆号:N/A
特异性:This antibody detects endogenous levels of AKT1 and does not cross-react with AKT2 and other proteins.
纯度:The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
形式：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
浓度：1mg/ml
- 说明书：
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
