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AMPKbeta 1 Mouse mAb
AMPKbeta 1 Mouse mAb
- 中文名称:
- AMPKbeta 1 Mouse mAb
- 英文名称:
- AMPKbeta 1 Mouse mAb
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA320364
- 规格:
- 0.04 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL
- 保存建议:
- 储存在-20摄氏度/1年
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human, Mouse, Rat, Monkey
- 应用:
- IHC (Immunohistochemistry), IP (Immunoprecipitation), ICC (Immunocytochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:N/A
克隆号:N/A
特异性:This antibody detects endogenous levels of AMPK beta 1 and does not cross-react with related proteins.
纯度:The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
形式:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
浓度:1mg/ml
- 说明书:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided