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PP2C alpha Antibody
PP2C alpha Antibody
- 中文名称：
- PP2C alpha Antibody
- 英文名称：
- PP2C alpha Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA328988
- 规格：
- 0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL|4x0.2 mL
- 保存建议：
- 收到后，可在-20摄氏度储存12个月。
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
Predicted Reactivity: Pig(100%), Bovine(100%), Horse(86%), Rabbit(100%), Dog(100%)
- 应用：
- ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:PP2C alpha Antibody detects endogenous levels of total PP2C alpha.
纯度:The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
浓度：1mg/ml
- 说明书：
Function: Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Post Translational Modifications: Isgylation negatively regulates its activity.N-myristoylation is essential for the recognition of its substrates for dephosphorylation.
Subcellular Location: Cytoplasm>Cytosol. Membrane>Lipid-anchor. Note: Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
Tissue Specificity: Highly expressed in heart and skeletal muscle.
Subunit Structure: Monomer (By similarity). Interacts with PAK6. Interacts with the phosphorylated form of IKBKB/IKKB.
Similarity: Belongs to the PP2C family.
