Phospho-IFNAR1 (Tyr466) Antibody-Phospho-IFNAR1 (Tyr466) Antibody-一抗检测抗体

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: Phospho-IFNAR1 (Tyr466) Antibody

Phospho-IFNAR1 (Tyr466) Antibody

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中文名称：: Phospho-IFNAR1 (Tyr466) Antibody

英文名称：: Phospho-IFNAR1 (Tyr466) Antibody

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA329289

规格：: 0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL|4x0.2 mL

保存建议：: 收到后，可在-20摄氏度储存12个月。

货期：: 6-8周

来源宿主：: Rabbit

反应种属：: Human, Mouse, Rat

应用：: ELISA (Peptide ELISA), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Phospho-IFNAR1 (Tyr466) Antibody detects endogenous levels of IFNAR1 only when phosphorylated at Tyr466.
Tissue Specificity: IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
纯度:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：1mg/ml

说明书：

Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).

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