Phospho-Catenin 1 (Ser320) Antibody-Phospho-Catenin 1 (Ser320) Antibody-一抗检测抗体

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: Phospho-Catenin 1 (Ser320) Antibody

Phospho-Catenin 1 (Ser320) Antibody

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中文名称：: Phospho-Catenin 1 (Ser320) Antibody

英文名称：: Phospho-Catenin 1 (Ser320) Antibody

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA329435

规格：: 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL

保存建议：: 收到后，可在-20摄氏度储存12个月。

货期：: 6-8周

来源宿主：: Rabbit

反应种属：: Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Xenopus (82%)

应用：: ELISA (Peptide ELISA), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Phospho-Catenin 1 (Ser320) Antibody detects endogenous levels of Catenin 1 only when phosphorylated at Ser320.
Tissue Specificity: Expressed in vascular endothelium. Melanocytes and melanoma cells primarily express the long isoform 1A, whereas keratinocytes express shorter isoforms, especially 3A. The shortest isoform 4A, is detected in normal keratinocytes and melanocytes, and generally lost from cells derived from squamous cell carcinomas or melanomas. The C-terminal alternatively spliced exon B is present in the p120ctn transcripts in the colon, intestine and prostate, but lost in several tumor tissues derived from these organs.
纯度:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：1mg/ml

说明书：

Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.

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