
-
RUNX2 Antibody
RUNX2 Antibody
- 中文名称:
- RUNX2 Antibody
- 英文名称:
- RUNX2 Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA329564
- 规格:
- 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL
- 保存建议:
- Store at -20°C.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Mouse, Rat
- 应用:
- ELISA, WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:N/A
同型:IgG
克隆号:N/A
特异性:RUNX2 Antibody detects endogenous levels of total RUNX2.
纯度:Peptide affinity purification
形式:IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
浓度:1mg/ml
- 说明书:
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.