Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody-Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody-一抗检测抗体

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: Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody

Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody

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中文名称：: Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody

英文名称：: Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA329722

规格：: 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL

保存建议：: 收到后，可在-20摄氏度储存12个月。

货期：: 6-8周

来源宿主：: Rabbit

反应种属：: Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (88%)

应用：: ELISA (Peptide ELISA), IHC (Immunohistochemistry), WB (Western Blot)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Phospho-HIPK1/2/3 (Tyr352/Tyr361/Tyr359) Antibody detects endogenous levels of HIPK1/2/3 only when phosphorylated at Tyr352/361/359.
Tissue Specificity: Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung.
纯度:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：1mg/ml

说明书：

Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).

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