Phospho-Progesterone Receptor (Ser345) Antibody-Phospho-Progesterone Receptor (Ser345) Antibody-一抗检测抗体

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: Phospho-Progesterone Receptor (Ser345) Antibody

Phospho-Progesterone Receptor (Ser345) Antibody

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中文名称：: Phospho-Progesterone Receptor (Ser345) Antibody

英文名称：: Phospho-Progesterone Receptor (Ser345) Antibody

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA329829

规格：: 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL

保存建议：: 收到后，可在-20摄氏度储存12个月。

货期：: 6-8周

来源宿主：: Rabbit

反应种属：: Human, Rat, Monkey
Predicted Reactivity: Pig (86%), Dog (86%)

应用：: ELISA (Peptide ELISA), ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Phospho-Progesterone Receptor (Ser345) Antibody detects endogenous levels of Progesterone Receptor only when phosphorylated at Ser345.
Tissue Specificity: In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region-specific responses to hormonal stimuli.
纯度:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：1mg/ml

说明书：

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Transrepressional activity may involve recruitment of corepressor NCOR2.Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

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