Phospho-DDR1 (Tyr796) Antibody-Phospho-DDR1 (Tyr796) Antibody-一抗检测抗体

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: Phospho-DDR1 (Tyr796) Antibody

Phospho-DDR1 (Tyr796) Antibody

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中文名称：: Phospho-DDR1 (Tyr796) Antibody

英文名称：: Phospho-DDR1 (Tyr796) Antibody

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA329903

规格：: 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL

保存建议：: 收到后，可在-20摄氏度储存12个月。

货期：: 6-8周

来源宿主：: Rabbit

反应种属：: Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (86%), Xenopus (100%)

应用：: ELISA (Peptide ELISA), ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Phospho-DDR1 (Tyr796) Antibody detects endogenous levels of DDR1 only when phosphorylated at Tyr796.
Tissue Specificity: Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A-431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin.
纯度:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：1mg/ml

说明书：

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

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