Phospho-Epo-R (Tyr426) Antibody-Phospho-Epo-R (Tyr426) Antibody-一抗检测抗体

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: Phospho-Epo-R (Tyr426) Antibody

Phospho-Epo-R (Tyr426) Antibody

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中文名称：: Phospho-Epo-R (Tyr426) Antibody

英文名称：: Phospho-Epo-R (Tyr426) Antibody

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA329908

规格：: 0.05 mL|0.1 mL|0.2 mL|2x0.2 mL|3x0.2 mL

保存建议：: 收到后，可在-20摄氏度储存12个月。

货期：: 6-8周

来源宿主：: Rabbit

反应种属：: Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Sheep (100%), Rabbit (100%), Dog (100%)

应用：: ELISA (Peptide ELISA), ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:Phospho-Epo-R (Tyr426) Antibody detects endogenous levels of Epo-R only when phosphorylated at Tyr426.
Tissue Specificity: Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early-stage erythroid progenitor cells.
纯度:The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
形式：Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
浓度：1mg/ml

说明书：

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

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