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PARP Polyclonal Antibody
PARP Polyclonal Antibody
- 中文名称：
- PARP Polyclonal Antibody
- 英文名称：
- PARP Polyclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA36796
- 规格：
- 0.02 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议：
- Store at -20 degree C or -80 degree C. Avoid freeze / thaw cycles
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human, Mouse
- 应用：
- FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Affinity purification
形式：PBS with 0.05% proclin300,50% glycerol,pH7.3.
浓度：N/A
- 说明书：
PARP, a 116 kDa nuclear poly (ADPribose) polymerase, appears to be involved in DNA repair in response to environmental stress (1). This protein can be cleaved by many ICElike caspases in vitro (2,3) and is one of the main cleavage targets of caspase3 in vivo (4,5). In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP aminoterminal DNA binding domain (24 kDa) from the carboxyterminal catalytic domain (89 kDa) (2,4). PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis (6).
